Tophi are tiny, chalk-colored, stone-like deposits of uric acid that gather beneath the pores and skin and so are most often located in pores and skin throughout the joints and on the outside with the ear.
Dengan mencegah serangan ini, anda dapat mengawal penyakit anda dan mengelakkan komplikasi gout kronik dan gout yang boleh menjejaskan kesihatan anda.
Two major types of drugs are made use of to treat gout: urate-lowering and anti-inflammatory medicine. Drugs like these support manage the symptoms related to gout attacks and stop foreseeable future flare-ups.
Jika anda mengalami serangan gout ringan, ubat OTC boleh membantu mengurangkan gejala. Namun, pastikan anda berbincang dengan ahli farmasi atau doktor sebelum menggunakannya.
The ACR notes that individuals are most enthusiastic for therapy throughout an exacerbation. Anti-inflammatory remedies which include colchicine or nonsteroidal anti-inflammatory medications (NSAIDs) should be continued for three to six months soon after setting up urate-reducing therapy.
Several remedies are productive for acute flare-ups. The success of minimal-dose colchicine is similar to that of substantial-dose colchicine with less adverse outcomes. NSAIDs and glucocorticoids are as productive as colchicine.
Sebaliknya, ubat ini umumnya tidak dapat digunakan jika anda mengalami masalah buah pinggang, terutama batu ginjal. Sebabnya, dengan meningkatkan kemampuan buah pinggang untuk menyaring asid urik, ini juga dapat meningkatkan risiko pembentukan batu ginjal.
Probenecid is minimally helpful, so take into consideration switching to febuxostat in lieu of adding probenecid for very poor control on the best tolerated dose of allopurinol.
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Gout adalah penyebab yang lazim bagi artritis keradangan (sakit, kemerahan, kepansan dan bengkak pada sendi yang terlibat) dan disebabkan pembentukan kristal-kristal urate sama ada di dalam ataupun di sekeliling sendi-sendi. Asid urik adalah bahan kumuhan yang biasanya dibuang bersama air kencing.
Selain itu, terdapat kajian yang menunjukkan potensinya dalam rawatan penyakit lain seperti sirosis hati dan penyakit Behçet, namun penggunaannya dalam kes ini lebih jarang.
Ketidakselesaan yang berlarutan. Setelah kesakitan yang paling teruk hilang, beberapa ketidakselesaan sendi mungkin berlangsung dari beberapa hari hingga beberapa minggu. Serangan kemudian mungkin akan bertahan lebih lama dan mempengaruhi lebih banyak sendi.
Dalam serangan gout, kristal asid urik yang tajam terkumpul di sekitar sendi, website menyebabkan sel imun bertindak balas secara agresif. Reaksi ini menyebabkan keradangan dan sakit.
Relevant: Where to turn for pain aid - acetaminophen or NSAIDs? Uric acid-lowering remedies The ACR pointers recommend treating gout with uric acid-decreasing remedies for people who have tophi (nodules that sort from the mass of uric acid crystals at joints or in gentle tissues), radiographic proof (X-ray or other imaging) of harm because of gout, kidney stones (people with gout have an elevated danger of kidney stones as uric acid crystals can sort kidney stones in a lot of people) or two or even more gout flares a year.